Hongbin Zhai
  • Education & Experience

    2015 - Present        Professor, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, China

    2010 - 2015            Professor and Director, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, China
    2000 - 2010            Professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China
    1998-2000              Postdoctoral Research Associate, with Professor Henry Rapoport, Department of Chemistry, University of California, Berkeley, California
    1996-1997              Postdoctoral Research Associate, with Professor Albert Soloway, College of Pharmacy, The Ohio State University, Columbus, Ohio
    1995                       Ph.D. Organic Chemistry , The Ohio State University, Columbus, Ohio
    1988                       M.S. Analytical Chemistry, Peking Union Medical College, Beijing
    1985                       B.S. Applied Chemistry, Peking University, Beijing
     
  • Awards & Honors

    1.  Lectureship Awards of Asian Core Program, “Cutting-Edge Organic Chemistry in Asia” (2013, 2012, 2011, 2008, 2006)

    2.  New century talents national candidates 新世纪百千万人才国家级人选(2009)
    3.  “Distinguished Young Investigator” Program, National Natural Science Foundation of China (2006)
    4.  “Post-Venus” Program, Science and Technology Commission of Shanghai Municipal (2005)
    5.  “Venus” Program, Science and Technology Commission of Shanghai Municipal (2002)
    6. “Hundreds of Talent” Program, Chinese Academy of Sciences (1999)
  • Research Fields

    1. Total synthesis of natural products
    2. Heterocyclic chemistry/medicinal chemistry
    3. Synthetic methodology development

  • Selected Publications

    1.  Chen, X.; Duan S.; Tao C.; Zhai H.*; Qiu, F. G.* Total Synthesis of (+)-Gelsemine via an Organocatalytic Diels-Alder Approach, Nat. Commun. 2015, DOI: 10.1038/ncomms8204.
    2.  Guo, J.-J.; Li, Y.; Cheng, B.; Xu, T.; Tao, C.; Yang, X.; Zhang, D.; Yan, G.; Zhai, H.* Expedient Construction of the [5-6-7] Tricyclic Core of Calyciphylline A-Type Alkaloids, Asian J. Chem. 2015, 10, 865.
    3.  Tian, J.; Du, Q.; Guo, R.; Li, Y.; Cheng, B.; Zhai, H.* Total Synthesis of Indole Alkaloid (±)-Subincanadine E, Org. Lett. 2014, 16, 3173.
    4.  Pan. Z.; Zheng, C.; Wang, H.; Chen, Y.; Li, Y.; Cheng, B.; Zhai, H.* Total Synthesis of (±)-Sculponeatin N, Org. Lett. 2014, 16, 216.
    5.  Xu, K.; Cheng, B.; Li, Y.; Xu, T.; Yu, C.; Zhang, J.; Ma, Z.; Zhai, H.* Stereocontrolled Total Syntheses of (±)-Fawcettimine, (±)-Lycoflexine, and (±)-Lycoflexine N-Oxide, Org. Lett. 2014, 16, 196.
    6.  Yang, Y.; Fu, X.; Chen, J.; Zhai, H.* Total Synthesis of (–)-Jiadifenin, Angew. Chem. Int. Ed. 2012, 51, 9825 (Collected in Synfacts 2012, 8, 1175).
    7.  Chen, J.; Gao, P.; Yu, F.; Yang, Y.; Zhu, S.; Zhai, H.* Total Synthesis of (±)-Merrilactone A, Angew. Chem. Int. Ed. 2012, 51, 5897 (Highlighted by Chin. J. Org. Chem. 2012, 32, 1759).
    8.  Xie, Y.; Wang, N.; Cheng, B.; Zhai, H.* Total Synthesis of (±)-Cephalosol, Org. Lett. 2012, 14, 3.
    9.  Cheng, B.; Wu, F.; Yang, X.; Zhou, Y.; Wan, X.; Zhai, H.* Efficient Total Synthesis of Marine Alkaloid (–)-Nakadomarin A, Chem.Eur. J. 2011, 17, 12569.
    10.  Zhang, W.; Luo, S.; Fang, F.; Chen, Q.; Hu, H.; Jia, X.; Zhai, H.* Total Synthesis of Absinthin, J. Am. Chem. Soc. 2005, 127, 18.