化学基因组学实验室

    北京大学深圳研究生院化学基因组学实验室筹建于2003年,2006年作为深圳大学城九家拟建国家重点实验室之一成为深圳市重点实验室。实验室目前拥有专职教师19人,其中有中国科学院院士1名、长江学者4名、鹏城学者2名和“双百计划”科技领军人才2名,博士生导师 8 人。
  
  化学基因组学重点实验室科研平台分为生物学、合成化学和理论计算化学三个部分,符合现代药物研发过程的最新趋势,可以利用化学基因组学的交叉学科研究策略实现实验室既定的发展目标,为深圳及我国的生物医药产业,尤其是具有自主知识产权的新药研发作出贡献。目前化学基因组学实验室已建成实验室面积超过3000平方米,总固定资产投资超过5000万元,购置了开展创新药物研究的关键仪器,其中包括500兆的超导核磁,高分辨质谱,MALDI-TOFTOF仪,X-光衍射仪,流式细胞仪,药物筛选平台等。
 
  化学基因组学重点实验室以抗癌和抗病毒药物研发为主要研究方向,开发具有自主知识产权的成果,以交叉学科研究为特色培养生物医药研发的优秀人才。通过组建一个具有国际竞争能力的化学基因组学研究平台和研究团队,结合深圳优势,提升深圳生物医药产业的源头创新做好人才和技术储备。化学基因组学实验室的建立是完善我国药物研究创新体系的重要标志之一。其目标是根据国际新药创新的发展趋势,采取新的运行机制和管理模式,建立以一流海外留学归国人员为主要研究骨干的跨学科研究和开发队伍,培养一批活跃在科学前沿的化学基因组学科研人才,使用国际上最新的技术以加速我国创新药物的研究进程。
 
    Chemical Genomics is a newly emerged multidisciplinary research area that concerns systematic study of biological targets using chemical probes and links together Synthetic Chemistry, Biochemistry, Genomic Sciences and High-Throughput Screening (HTS) technologies. Key Laboratory of Chemical Genomics was established with funds from both SZPKU and Shenzhen Municipal Government in 2006 and has been accredited as a Guangdong Province Key Laboratory in 2007. Leveraging on the universe of resources of PKU and economic strength of the greater Shenzhen-Hong Kong metro area, Laboratory of Chemical Genomics is committed to excellence and leadership in both scientific research and graduate education. During the past three years, Key Laboratory of Chemical Genomics has spent tremendous efforts in recruiting accomplished scholars and educators to its faculty from around the world and in developing the-state-of-the-art infrastructure capable of supporting multidisciplinary biomedical research, particularly in the areas critical to drug discovery and development, such as synthetic organic chemistry, medicinal chemistry, chemical biology, structural biology, molecular and cell biology, developmental biology, combinatorial screening methodology, computational chemistry, and bioinformatics.


 
     Under a conceptually new framework that effectively breaks down the traditional boundary and integrates scientists of various disciplines under one roof, Key Laboratory of Chemical Genomics is devoted to discovering and developing new generation of medicines that could help address some of the most critical medical needs, particularly in the anti-viral and anti-cancer areas, through orchestrated efforts of our independent yet highly cooperative research groups. Key Laboratory of Chemical Genomics is also playing an increasingly important role in educating and inspiring some of China’s brightest young minds to better serve the nation’s rapidly advancing biotech and pharmaceutical industries. Our innovative graduate program, representing the first of its kind in China, is carefully designed to give students multidisciplinary yet focused training in the above core areas while at the same time maintaining a standard as rigorous as that of a classical PKU education in more traditional disciplines.
 
Key Laboratory of Chemical Genomics 
2009-05-13