黄湧
  • 教育背景及工作经历

    2009-至今         北京大学深圳研究生院,教授
    2004-2009        美国默克集团(Merck KGaA),高级研发科学家
    2002-2004        加州理工学院 (导师: David W. C. MacMillan), 博士后
    1997-2002        芝加哥大学 (导师: Viresh H. Rawal),理学博士
    1993-1997        北京大学 (导师: Xiulin Ye), 理学学士
     

  • 奖项及荣誉
    2014        Asia Core Program Lectureship Award (Korea)
    2014        罗氏中国青年科学家奖
    2014        Bayer Investigator Award
    2014        ACS and Organic Letters “Outstanding Author of the Year”
    2014        深圳市杰出教师
    2013        Asia Core Program Lectureship Award (Japan and Thailand)
    2013        教育部新世纪优秀人才
  • 研究兴趣

    化学反应的立体及化学选择性控制,是有机不对称合成方法学的主要挑战。本课题组旨在发展具有高效选择性的不对称催化策略,用以直接构建结构多样性的杂环化合物,并将其应用于天然产物全合成、药物化学以及化学生物学研究领域。

  • 代表性成果

    1.   Leifeng Wang, Fengjin Wu, Jiean Chen, David A. Nicewicz*, Yong Huang* “Visible-Light-Mediated [4+2] Cycloaddition of Styrenes: Synthesis of Tetralin Derivatives” Angew. Chem. Int. Ed. 2017, 56, 6896.

    2.   Jiean Chen, Pengfei Yuan, Leming Wang, Yong Huang* “Enantioselective β-Protonation of Enals via a Shuttling Strategy” J. Am. Chem. Soc. 2017, 139, 7045.

    3.   Hao Jiang, Li-Ping Xu, Yan Fang, Zhen-Xing Zhang, Zhen Yang,* Yong Huang* “A Migratory Ether Formation Route to Medium-Sized Sugar Mimetics” Angew. Chem. Int. Ed. 2016, 55, 14340.

    4.   Leming Wang, Jiean Chen, Yong Huang* “Highly Enantioselective Aza-Michael Reaction between Alkyl Amines and β-Trifluoromethyl β-Aryl Nitroolefins” Angew. Chem. Int. Ed. 2015, 54, 15414.

    5.   Chaosheng Luo, Zhen Wang, Yong Huang* “Asymmetric Intramolecular a-Cyclopropanation of Aldehydes Using a Donor/Acceptor Carbene Mimetic” Nat. Commun. 2015, 6, 10041.

    6.   Xijian Li, Siyu Peng, Li Li, Yong Huang* “Synthesis of tetrasubstituted 1-silyloxy-3-aminobutadienes and chemistry beyond Diels–Alder reactions” Nat. Commun. 2015, 6, 6913.

    7.   Zhaofeng Wang, Li Li, Yong Huang* “A General Synthesis of Ynones from Aldehydes via Oxidative C–C bond Cleavage under Aerobic Conditions” J. Am. Chem. Soc. 2014, 136, 12233.

    8.   Ying Chen, Dongqi Wang, Pingping Duan, Rong Ben, Lu Dai, Xiaoru Shao, Mei Hong, Jing Zhao*, Yong Huang* “A multitasking functional group leads to structural diversity using designer C–H activation reaction cascades” Nat. Commun. 2014, 5, 5610.

    9.   Jiean Chen, Yong Huang* “Asymmetric Catalysis with N-Heterocyclic Carbenes as Non-Covalent Chiral Templates” Nat. Commun. 2014, 5, 3437.

    10.  Zhaofeng Wang, Xijian Li, Yong Huang* “Direct α-Vinylidenation of Aldehydes and Subsequent Cascade: Gold and Amine Catalysts Work Synergistically” Angew. Chem. Int. Ed. 2013, 52, 14219.

    11.  Chaosheng Luo, Yong Huang* “A Highly Diastereo- and Enantioselective Synthesis of Tetrahydroquinolines: Quaternary Stereogenic Center Inversion and Functionalization” J. Am. Chem. Soc. 2013, 135, 8193.

    12.  Chengming Wang, Huan Sun, Yan Fang, Yong Huang* “General and Efficient Synthesis of Indoles through Triazene-Directed C–H Annulation” Angew. Chem. Int. Ed. 2013, 52, 5795.

    13.  Chengming Wang, Hu Chen, Zhaofeng Wang, Jiean Chen, Yong Huang* “Rhodium(III)-Catalyzed CH Activation of Arenes Using a Versatile and Removable Triazene Directing Group” Angew. Chem. Int. Ed. 2012, 51, 7242.