张欣豪
  • 张欣豪

  • 职务:副课题组长, 副教授
  • 电话:+86-0755-26037219
  • 邮箱:zhangxh@pkusz.edu.cn
  • 课题组主页:http://web.pkusz.edu.cn/wu/
  • 教育背景及工作经历
    2011 -                 副教授,博导 北京大学深圳研究生院
    2008 - 2010        洪堡学者,柏林工业大学 (Technische Universität Berlin),物理有机化学,导师: Prof. Dr. Drs. h.c. Helmut Schwarz
    2002 - 2007        博士,香港科技大学,理论有机化学,导师: 吴云东 院士
    1998 - 2002        学士(化学),中国科学技术大学
  • 奖项及荣誉

    2012                   深圳市海外高层次人才
    2012                   深圳市高层次人才—地方领军人才
    2008 - 2010        亚历山大∙冯∙洪堡奖学金
    1999 - 2001        中国科大优秀奖学金
    1999                   可口可乐杯——中国科大第10届辩论赛冠军

  • 研究兴趣

    结合质谱与计算化学方法于:
    1.  理解各类催化反应机理及筛选新催化剂
    2.  建立金属离子-生物小分子结合能的数据库并发展新的无机力场和过渡态力场
    3.  研究蛋白质-配体相互作用及设计新型无机药物
    4.  开发气相中的手性分子识别

  • 代表性成果

    1.  Shengtao Ding, Li-Juan Song, Yong Wang, Xinhao Zhang,* Lung Wa Chung,* Yun-Dong Wu,* Jianwei Sun,* Highly Regio- and Stereoselective Hydrosilylation of Internal Thioalkynes under Mild Conditions Angew. Chem. Int. Ed. 201554, 5632
    2.  Fengtao Zhou, Gui-Juan Cheng, Wenqiang Yang, Yan Long, Shasha Zhang, Yun-Dong Wu, Xinhao Zhang,* Qian Cai* Enantioselective Formation of Cyano-Bearing All-Carbon Quaternary Stereocenters: Desymmetrization by Copper-Catalyzed N-Arylation. Angew. Chem. Int. Ed. 201453, 9555
    3.  Gui-Juan Cheng, Yun-Fang Yang, Peng Liu, Ping Chen, Tian-Yu Sun, Gang Li, Xinhao Zhang, Ken N. Houk,* Jin-Quan Yu,* Yun-Dong Wu,* Role of N-Acyl Amino Acid Ligands in Pd(II)-Catalyzed Remote C–H Activation of Tethered Arenes J. Am. Chem. Soc. 2014136, 894.
    4.  Yun-Fang Yang, Gui-Juan Cheng, Peng Liu, Dasheng Leow, Tian-Yu Sun, Ping Chen, Xinhao Zhang, Jin-Quan Yu,* Yun-Dong Wu,* Ken N. Houk,* Palladium-Catalyzed meta-Selective C–H Bond Activation with a Nitrile-Containing Template: A Computational Study on Mechanism and Origins of Selectivity J. Am. Chem. Soc. 2014136, 344.
    5.  Yun-Fang Yang, Gui-Juan Cheng, Jun Zhu, Xinhao Zhang,* Shigeyoshi Inoue,* and Yun-Dong Wu* " Silicon-Containing Formal 4π-Electron Four-Membered Ring Systems: Antiaromatic, Aromatic, or Nonaromatic? " Chem. Eur. J.201218, 7516-7524.
    6.  Kai Chen, Zhe-Chen Wang, Maria Schlangen, Yun-Dong Wu, Xinhao Zhang,* Helmut Schwarz* "Thermal Activation of Methane and Ethene by Bare MO.+ (M=Ge, Sn, and Pb): A Combined Theoretical/Experimental Study " Chem. Eur. J.201117, 9619-9625. (Cover)