卢  菲
  • 教育背景及工作经历

    教育背景:
    2002.09-2008.07        理学博士,细胞生物学专业 北京大学生命科学学院
    1989. 09-1993.07       理学学士,生物学专业 新疆师范大学生物系
    工作经历:
    2011.9-今                    副教授,博士生导师 北京大学深圳研究生院,化学生物学与生物技术学院
    2008.12-2012.01        博士后 美国内华达肿瘤研究所张慧教授实验室
    2009.9-2011.9            石河子大学副教授
    1999.9-2009.9            石河子大学讲师
    1993.7-1999.9            石河子大学助教

  • 代表性成果

    1. Feng Yin, Chengbin Yang, Qianqian Wang, Shuwen Zeng, Rui Hu, Guimiao Lin, Jinglin Tian, Siyi Hu, Rong Feng Lan, Ho Sup Yoon, Fei Lu*, Kuan Wang*, and Ken-Tye Yong*. A Light-Driven Therapy of Pancreatic Adenocarcinoma Using Gold Nanorods-Based Nanocarriers for Co-Delivery of Doxorubicin and siRNA. Theranostics 5(8), 818-833. 2015. (Co-corresponding author)
    2. Feng Yin, Rongfeng Lan, Xiaoming Zhang, Linyu Zhu, Fangfang Chen, Zhengshuang Xu, Yuqing Liu, Tao Ye, Hong Sun, Fei Lu * and Hui Zhang. * LSD1 Regulates Pluripotency of Embryonic Stem/Carcinoma Cells through HDAC1-mediated eacetylation of Histone H4 at Lysine 16. Molecular and Cellular Biology, 34(2), 158-179. 2014. (Co-corresponding author)
    3. Xiaoming Zhang, Fei Lu, Jing Wang, Feng Yin, Zhengshuang Xu, Dandan Qi, Xianhui Wu, Yuwen Cao, Weihua Liang, Yuqing Liu, Hong Sun, Tao Ye, and Hui Zhang. Pluripotent Stem Cell Protein Sox2 Confers Sensitivity towards LSD1 Inhibition in Cancer Cells. Cell Reports, 5, 445-457, 2013. (Co-first author
    4. Rongfeng Lan, Guimiao Lin, Feng Yin, Jun Xu, Xiaoming Zhang, Jing Wang, Yanchao Wang, Jianxian Gong, Yuan-Hua Ding, Zhen Yang, Fei Lu* and Hui Zhang. * Dissecting the Phenotypes of Plk1 Inhibition in Cancer Cells Using Novel Kinase Inhibitory Chemical CBB2001. Laboratory Investigation.92, 1503-1514, 2012. (Co-corresponding author)
    5. Jing Wang, Fei Lu, Qi Ren, Hong Sun, Zhengshuang Xu, Rongfeng Lan, Yuqing Liu, David Ward, Junmin Quan, Tao Ye,, and Hui Zhang*. Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties. Cancer Research 71:7238-7249. 2011. (Co-first author)
    6. Fei Lu, Rongfeng Lan, Hongyin Zhang, Qing Jiang and Chuanmao Zhang*. Geminin is partially localized to centrosome and plays a role in proper centrosome duplication. Biology of the Cell 101, 273–285, 2009.
    7. Fei Lu and Hui Zhang*. Chapter 6, Targeting Non-Acetylation Histone Erasers, in Epigenetics and Drug Discovery, edited by Nessa Carey, published by the Royal Society of Chemistry, Cambridge, United Kingdom, in press.
    8. 黄世娇,卢菲, 张传茂*: 第22章 真核生物DNA 复制的起始调控,《分子细胞生物学》(陈晔光,张传茂,陈佺主编)第二版, 清华大学出版社,2011.
    卢菲, 张传茂*: 真核生物DNA 复制的起始调控,《分子细胞生物学》(陈晔光,张传茂,陈佺主编),清华大学出版社, 2006.
    9. Xiaofeng Zheng, Xueyu Dai, Yanmei Zhao, Qiang Chen, Fei Lu, Deqiang Yao, Quan Yu, Xinping Liu, Chuanmao Zhang, Xiaocheng Gu, and Ming Luo*. Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. (2007) Proc. Natl. Acad. Sci. USA 104(21): 8809–8814.
    10. Hui Ren, Liya Wang, Matthew Bennett, Yuhe Liang, Xiaofeng Zheng, Fei Lu, Lanfen Li, Jie Nan, Ming Luo,Staffan Eriksson, Chuanmao Zhang, and Xiao-Dong Su*. The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus. (2005) Proc. Natl. Acad. Sci. USA, 102(2): 303–308.