On June 13, 2018, with the invitation of Prof. Huang Yong, Prof. Michael P. Doyle from University of Texas at San Antonio visited our school and gave a wonderful lecture titled “Asymmetric Catalytic Constructions of Heterocycles and Carbocycles by Cycloaddition”in E104, teachers and students of our school actively participated in the academic discussions and exchanged ideas.
Firstly, Prof. Doyle introduced historical scope of electrophilic metal carbene reactions and the basic mechanism for metal carbene reactions. Then, Prof. Doyle showed a series of cycloaddition reactions, which developed by their lab, via metal carbene to asymmetrically synthesize heterocycles and carbocycles. Such as, [3+3], [3+2], [3+1]-cycloaddition, etc. These cycloaddition reactions between can be constructed from dipole of metal carbene, which generated from enoldiazoacetates react with metal compound, with another corresponding compound.
After the speech, professors and students of our school discussed with Prof. Doyle actively. Then, Prof. Doyle then had a lunch meeting with students. In the symposium, Prof. Doyle not only answered the students some problems about the chemical research, also introduced the scientific life in the USA to students, and encouraged the students to follow their own research interests and preserve in it , which made the students benefit a lot.（Written by En Li；Photoed by En Li）
Brief introduction of speaker:
Education:
Ph. D. in Chemistry; Iowa State University;
B. S. in Chemistry; College of St. Thomas.
Professional associations:
Prof. Doyle, the Rita and John Feik Distinguished University Chair in Medicinal Chemistry at the University of Texas at San Antonio, has had academic appointments at undergraduate institutions (Hope College and Trinity University) and graduate universities (University of Arizona and University of Maryland), as well as being Vice President, then President, of a science foundation before taking his current position.
Current research interests:
Catalytic oxidation processes
Design and development of chiral catalysts
Diazo chemistry
Highly enantioselective catalytic reactions
Medicinal chemistry
