2016年6月7日,美国俄亥俄州立大学的裴德华教授应我院李子刚副教授邀请访问我院并以题为“Drug the undruggable targets with cyclic peptides”在E-104报告厅为我院师生作了精彩的学术报告。
裴德华教授致力于发展大环多肽类分子靶向细胞内蛋白-蛋白相互作用。利用组合化学手段筛选针对细胞内难以靶向的蛋白-蛋白相互作用的高亲和力的单环以及多环的多肽,同时裴德华教授发展了基于环肽的具有极高穿膜能力的穿膜肽,同时系统地研究环肽穿膜机制,提出了环肽新的入胞机制。
我院师生积极与其进行学术讨论与交流,获益匪浅。
裴德华教授介绍:
Dehua Pei obtained his B.S. Degree in Chemistry from Wuhan University, China in 1986 and his Ph.D. Degree in Organic Chemistry from University of California, Berkeley in 1991, working under the direction of Peter G. Schultz. After a postdoctoral stint with Christopher T. Walsh at Harvard Medical School, he joined the faculty at OSU in 1995 as an Assistant Professor. He was promoted to Associate Professor of Chemistry in 2001 and Professor of Chemistry in 2004.