2008.09-2012.07 北京大学化学学院，理学学士

2012.09-2018.06 北京大学化学学院，理学博士，有机化学专业

2018.07-2019.10 北京大学化学学院，研究助理

2019.11-2022.06 Scripps研究所，博士后

2022.07-2024.11 Rice University，博士后

   课题组主要开展化学酶法合成方向研究，涉及有机合成化学、酶化学、分子生物学和生物信息学领域。主要目标包括：（1）挖掘、验证酶的反应性，探究其催化机制；（2）对酶进行改造，改进反应性与底物适用范围，发展酶催化方法学；（3）将酶促反应应用于有机合成中，实现有价值分子的化学-酶法合成。

(1) Jiang, Y.-L.;# Yu, X.-R.;# Renata, H.* Concise Synthesis of Fostriecin and Analogs through Late-Stage Chemoenzymatic Installation of Their Key Pharmacophores. ChemRxiv. DOI: 10.26434/chemrxiv-2025-c4zc6.

(2) Jiang, Y.-L.; Renata, H.* Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids. Nat. Chem. 2024, 16, 1531.

(3) Jiang, Y.-L.; Renata, H.* Finding superior biocatalysts via homolog screening. Chem. Catal. 2022, 2, 2471.

(4) Jiang, Y.-L.; Yu, H.-X.; Li, Y.; Qu, P.; Han, Y.-X.; Chen, J.-H.;* Yang, Z.* Asymmetric total synthesis of pre-schisanartanin C. J. Am. Chem. Soc. 2020, 142, 573.

(5) Han, Y.-X.;# Jiang Y.-L.;# Li, Y.; Yu, H.-X.; Tong, B.-Q.; Niu, Z.; Zhou, S.-J.; Liu, S.; Lan, Y.;* Chen, J.-H.;* Yang, Z.* Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A. Nat. Commun. 2017, 8, 14233. (#equal contribution)

(6) Zhai, Y.; Huang, X.; Zhang, K.; Huang, Y.; Jiang, Y.; Cui, J.; Zhang, Z.; Chiu, C. K. C.; Zhong, W.; Li, G.* Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling. Nat. Commun. 2022, 13, 4906.

(7) Sun, T.-W.; Liu, D.-D.; Wang, K.-Y.; Tong, B.-Q., Xie, J.-X., Jiang, Y.-L.; Li, Y.; Zhang, B.; Liu, Y.-F.; Wang, Y.-X.; Zhang, J.-J.; Chen, J.-H.;* Yang, Z.* Asymmetric total synthesis of lancifodilactone G acetate. 1. diastereoselective synthesis of CDEFGH ring system. J. Org. Chem. 2018, 83, 6893.

(8) Liu, D.-D.#; Sun, T.-W.#; Wang, K.-Y.; Lu, Y.; Zhang, S.-L.; Li, Y.-H.; Jiang, Y.-L.; Chen, J.-H.;* Yang, Z.* Asymmetric total synthesis of lancifodilactone G acetate. J. Am. Chem. Soc. 2017, 139, 5732.

Patents

Renata, H.; Jiang, Y. Synthesis of cotylenin and analogs thereof for the development of selective modulators of 14-3-3 protein-protein interaction. WIPO number: WO 2024/050554 A2.