各位老师和同学：
大家好，2026年4月22日（星期三），化学生物学与生物技术学院邀请了新加坡南洋理工大学陈俊丰院士到访我院并进行化学生物学前沿讲座，欢迎大家参加！
嘉 宾：陈俊丰院士
嘉宾单位：新加坡南洋理工大学
主 题：手性胍盐离子对催化
时 间：2026年4月22日（星期三）11：00-12：30
地 点：C102
邀请人：周建荣
讲座摘要：
Chiral cations have demonstrated exceptional efficacy as phase-transfer catalysts, particularly in conjunction with inorganic basic salts like hydroxides and carbonates in base-mediated reactions. Over the past decade, we have developed several chiral cation catalysts, notably pentanidium and bisguanidinium, which have significantly advanced the field. In this report, we explore their roles in ion-pair catalysis using three distinct types of anions. First, we examine the use of fluoride to generate hypervalent silicate intermediates and its pairing with chiral cations to facilitate enantioselective reactions. Next, we delve into reactions where chiral cations work synergistically with polyoxometalates, such as tungstate and molybdate, serving as co-catalysts. Lastly, we highlight the ability of chiral cations to modulate reactions involving anionic organic sulfur salts. Key transformations, including SN2X (halogenophilic nucleophilic substitution) and the desymmetrization of sulfinates, will be discussed in detail.
嘉宾简介：
Prof. Tan received his BSc (Hons), First Class from the National University of Singapore in 1995 and completed his PhD from the University of Cambridge in 1999. Following that, he carried out two years postdoctoral training at the Department of Chemistry and Chemical Biology, Harvard University. Subsequently, he worked as a Research Associate at Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School for another year before joined the Department of Chemistry, National University of Singapore as Assistant Professor in 2003. He was then promoted to Associate Professor in 2010. He joined Nanyang Technological University in 2012 as an Associate Professor and was promoted to Full Professor in 2016. He is currently the President’s Chair Professor of Organic Chemistry at NTU. His research interest is in the field of Synthetic Organic Chemistry and Catalysis.
Professor Tan is current President of the Singapore National Academy of Science and the immediate past President of Singapore National Institute of Chemistry. He was elected to the Singapore National Academy of Science in 2020. He is recently named the recipient of the 2023 Ta-Shue Chou Lectureship Award and gave the Grubbs Institute Distinguished Lecture at the Grubbs Institute in 2024.
请注意：本次讲座需要化学方向学生签到！
