神经突触的形成和维持功能的分子基础，以及神经突触结构/功能障碍在神经和精神疾病中作用机理。
发表文章（#：共同第一；*：共同通讯）
1) Qin, L*, Liu, Z.*, Guo, S., Han, Y., Wang, X., Ren, W., Chen, J., Zhen, H., Nie, C., Xing, K., Chen, T., Südhof TC*, Sun, Y.*,Zhang, B*. (2024). Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number.Molecular Psychiatry.https://doi.org/10.1038/s41380-024-02659-6（最后通讯作者）
2) Lloyd, B.A., Han, Y., Roth, R.,Zhang, B., Aoto, J*. (2023). Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.Nature Communications. 14, 4706.https://doi.org/10.1038/s41467-023-40419-2
3) Zhu, F. #, Liu, L. #, Li, J. #, Liu, B., Wang, Q., Jiao R., Xu, Y., Wang, L., Sun, S., Sun, X., Younus, M., Wang, C., Hokfel, T.,Zhang, B.*, Gu, H. *, Xu, Z. *, Zhou, Z. *. (2022). Cocaine increases quantal norepinephrine secretion through NET-dependent PKC activation in locus coeruleus neurons.Cell Reports. 40(7), 16 August 2022, 111199.https://doi.org/10.1016/j.celrep.2022.111199(共同通讯作者)
4) Han, Y#, Cao, R#, Qin, L., Chen, L., Tang, A., *, Südhof, TC*,Zhang, B*. (2022) Neuroligin-3 confines AMPA-receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses.Science Advances. 8(24):eabo4173.https://www.science.org/doi/10.1126/sciadv.abo4173(最后通讯作者)
5) Qin, L., Guo, S., Han, Y., Wang, X.,Zhang, B*. (2020) Functional mosaic organization of neuroligins in neuronal circuits.Cellular and Molecular Life Sciences. 77, 3117-3127.https://doi.org/10.1007/s00018-020-03478-y(最后通讯作者)
6) Zhang, B.*,Gokce, O., Hale, D., Brose, N., Südhof, TC. (2018) Autism-associated Neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.Journal of Experimental Medicine. 215 (6): 1543-1553(唯一通讯作者)
7) Zhang, B.*,Seigneur, E., Wei, P., Gokce, O., Morgan, J., Südhof, TC. (2017) Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held.Molecular Psychiatry. 22, 1483–1491.[F1000 recommended](唯一通讯作者)
8) Zhang, B.*, Südhof, TC. (2016). Neuroligins are selectively essential for NMDA-receptor signaling in cerebellar stellate interneurons. J.Neurosci. 36(35):9070-9083.[F1000 recommended].(唯一通讯作者)
9) Zhang, B.#, Chen, L. #, Maxeiner, S., Lee, S., Gokce, O., Südhof, TC*. (2015) Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.Neuron. 87(4):781-96.[Cover Story]
